Genetic Polymorphism and Population Genetic Structure Analysis of 21 Autosomal STR Loci for a Han-Chinese Population from Luzhou of Southwest China

The Han nationality is an ancient and populous people, different places in China may have their distinct group relationships. Luzhou area, as a crossroads of several provinces Southwest China, lacks autosomal short tandem repeat (STR) research population genetics research. In this study, 21 STR loci were evaluated 1959 Han-Chinese individuals from area. There was no substantial linkage disequilibrium (LD) among the markers, all markers Hardy–Weinberg equilibrium (HWE). total discrimination power (TDP) cumulative probability exclusion (CPE) calculated to be 1–9.8505 × 10−16 1–1.9406 10−9, respectively. 333 alleles for STRs with allelic frequencies ranging 0.00026 0.51302, number ranged 7 locus TPOX 29 Penta E. According results comparison differentiation, historical influences, geographical distribution, cultural integration, economic development impact on other Chinese populations. These found enrich information forensic databases provide highly informative polymorphisms our practice including personal identification parentage testing.